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A discussion of stem cell in the human body

  1. First, they are unspecialized cells capable of renewing themselves through cell division , sometimes after long periods of inactivity.
  2. Much work lies ahead. This new type of stem cell, called induced pluripotent stem cells iPSCs , will be discussed in a later section of this document.
  3. Sources of Stem Cells Much of the public discussion about stem cells has focused on where stem cells come from.

Where can I get more information? What are stem cells, and why are they important? Stem cells have the remarkable potential to develop into many different cell types in the body during early life and growth.

Using Stem Cells to Save People

In addition, in many tissues they serve as a sort of internal repair system, dividing essentially without limit to replenish other cells as long as the person or animal is still alive. When a stem cell divides, each new cell has the potential either to remain a stem cell or become another type of cell with a more specialized function, such as a muscle cell, a red blood cell, or a brain cell.

What is a Stem Cell?

Stem cells are distinguished from other cell types by two important characteristics. First, they are unspecialized cells capable of renewing themselves through cell divisionsometimes after long periods of inactivity.

  • Some revolutionary treatments for blindness, MS, stroke and spinal cord injury are already in early stage clinical trials;
  • The tissue in our skin needs constant renewal that could not take place without stem cells;
  • Stem cell research is one of the most fascinating areas of contemporary biology, but, as with many expanding fields of scientific inquiry, research on stem cells raises scientific questions as rapidly as it generates new discoveries.

Second, under certain physiologic or experimental conditions, they can be induced to become tissue- or organ-specific cells with special functions. In some organs, such as the gut and bone marrow, stem cells regularly divide to repair and replace worn out or damaged tissues. In other organs, however, such as the pancreas and the heart, stem cells only divide under special conditions.

Until recently, scientists primarily worked with two kinds of stem cells from animals and humans: The functions and characteristics of these cells will be explained in this document. Scientists discovered ways to derive embryonic stem cells from early mouse embryos more than 30 years ago, in 1981. The detailed study of the biology of mouse stem cells led to the discovery, in 1998, of a method to derive stem cells from human embryos and grow the cells in the laboratory. These cells are called human embryonic stem cells.

Stem Cell Basics I.

The embryos used in these studies were created for reproductive purposes through in vitro fertilization procedures. When they were no longer needed for that purpose, they were donated for research with the informed consent of the donor.

In 2006, researchers made another breakthrough by identifying conditions that would allow some specialized adult cells to be "reprogrammed" genetically to assume a stem cell-like state. This new type of stem cell, called induced pluripotent stem cells iPSCswill be discussed in a later section of this document.

Stem cells are important for living organisms for many reasons. In the 3- to 5-day-old embryo, called a blastocystthe inner cells give rise to the entire body of the organism, including all of the many specialized cell types and organs such as the heart, lungs, skin, sperm, eggs and other tissues.

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In some adult tissues, such as bone marrow, muscle, and brain, discrete populations of adult stem cells generate replacements for cells that are lost through normal wear and tear, injury, or disease. Given their unique regenerative abilities, stem cells offer new potentials for treating diseases such as diabetes, and heart disease.

However, much work remains to be done in the laboratory and the clinic to understand how to use these cells for cell-based therapies to treat disease, which is also referred to as regenerative or reparative medicine.

  1. In other words, stem cells have the power to heal. Scientists discovered ways to derive embryonic stem cells from early mouse embryos more than 30 years ago, in 1981.
  2. This new type of stem cell, called induced pluripotent stem cells iPSCs , will be discussed in a later section of this document. The functions and characteristics of these cells will be explained in this document.
  3. In 2006, researchers made another breakthrough by identifying conditions that would allow some specialized adult cells to be "reprogrammed" genetically to assume a stem cell-like state. Researchers are finding new ways to use stem cells to rebuild tissue in many parts of the body where it has been damaged, such as the eye, the pancreas and the brain.
  4. Stem cells are important for living organisms for many reasons.
  5. These are called pluripotent stem cells.

Scientists are already using stem cells in the laboratory to screen new drugs and to develop model systems to study normal growth and identify the causes of birth defects. Research on stem cells continues to advance knowledge about how an organism develops from a single cell and how healthy cells replace damaged cells in adult organisms.

Stem cell research is one of the most fascinating areas of contemporary biology, but, as with many expanding fields of scientific inquiry, research on stem cells raises scientific questions as rapidly as it generates new discoveries.